Professor Andrew Jackson
We are a multidisciplinary research group that uses genetic, biochemical, cellular, immunological and developmental approaches to gain new insights into fundamental biological processes and advance the understanding of disease mechanisms.
Lagging-strand replication shapes the mutational landscape of the genome.
Reijns et al, Nature (2015)
Mutations in PLK4, encoding a master regulator of centriole biogenesis, cause microcephaly, growth failure and retinopathy. Martin et al, Nature Genetics (2014)
- Cerebral organoids model human brain development and microcephaly. Lancaster et al, Nature (2013)
- Ribonucleotides are the most common lesions in genomic DNA. Reijns et al, Cell (2012)
We are looking to recruit talented scientists to join our research team. If you are interested in joining the lab please contact Andrew Jackson with a copy of your CV.