Professor Andrew Jackson
We are a multidisciplinary research group that uses genetic, biochemical, cellular, immunological and developmental approaches to gain new insights into fundamental biological processes and advance the understanding of disease mechanisms.
Latest findings
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cGAS surveillance of micronuclei links genome instability to innate immunity
July 2017 – Nature
DOI: 10.1038/nature23449 - Mutations in DONSON disrupt replication fork stability and cause microcephalic dwarfism.
Apr 2017 – Nature Genetics
DOI: doi:10.1038/ng.3790 - Mutations in genes encoding condensin complex proteins cause microcephaly through decatenation failure at mitosis
Oct 2016 – Genes & Development
DOI: 10.1101/gad.286351.116 - Ribonuclease H2 mutations induce a cGASSTING-dependent innate immune response
Apr 2016 – EMBO Journal
DOI: 10.15252/embj.201593339 - TRAIP promotes DNA damage response during genome replication and is mutated in primordial dwarfism
Jan 2016 – Nature Genetics
DOI: doi:10.1038/ng.3451 - Lagging-strand replication shapes the mutational landscape of the genome
Jan 2015 – Nature, Vol: 518, Page(s): 502-506
DOI: 10.1038/nature14183
Positions Available
We are looking to recruit talented scientists to join our research team. If you are interested in joining the lab please contact Andrew Jackson with a copy of your CV.
andrew.jackson@igmm.ed.ac.uk