Professor Andrew Jackson

We are a multidisciplinary research group that uses genetic, biochemical, cellular, immunological and developmental approaches to gain new insights into fundamental biological processes and advance the understanding of disease mechanisms.

Latest findings

• Mutations in TOP3A Cause a Bloom Syndrome-like Disorder.
  July 2018 Am J Hum Genet
  DOI: 10.1016/j.ajhg.2018.07.001
• CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions 
  July 2018 – Nature
  doi: 10.1038/s41586-018-0291-z

• cGAS surveillance of micronuclei links genome instability to innate immunity 
  July 2017 – Nature
  DOI: 10.1038/nature23449

• Mutations in DONSON disrupt replication fork stability and cause microcephalic dwarfism.
  Apr 2017 – Nature Genetics
  DOI: doi:10.1038/ng.3790
• Mutations in genes encoding condensin complex proteins cause microcephaly through decatenation failure at mitosis
  Oct 2016 – Genes & Development
  DOI: 10.1101/gad.286351.116

Positions Available

We are looking to recruit talented scientists to join our research team. If you are interested in joining the lab please contact Andrew Jackson with a copy of your CV.

andrew.jackson@igmm.ed.ac.uk