Professor Andrew Jackson

We are a multidisciplinary research group that uses genetic, biochemical, cellular, immunological and developmental approaches to gain new insights into fundamental biological processes and advance the understanding of disease mechanisms.

Latest findings

• cGAS surveillance of micronuclei links genome instability to innate immunity 
  July 2017 – Nature
  DOI: 10.1038/nature23449

• Mutations in DONSON disrupt replication fork stability and cause microcephalic dwarfism.
  Apr 2017 – Nature Genetics
  DOI: doi:10.1038/ng.3790
• Mutations in genes encoding condensin complex proteins cause microcephaly through decatenation failure at mitosis
  Oct 2016 – Genes & Development
  DOI: 10.1101/gad.286351.116
• Ribonuclease H2 mutations induce a cGASSTING-dependent innate immune response
  Apr 2016 – EMBO Journal
  DOI: 10.15252/embj.201593339
• TRAIP promotes DNA damage response during genome replication and is mutated in primordial dwarfism
  Jan 2016 – Nature Genetics
  DOI: doi:10.1038/ng.3451
• Lagging-strand replication shapes the mutational landscape of the genome
  Jan 2015 – Nature, Vol: 518, Page(s): 502-506
  DOI: 10.1038/nature14183

Positions Available

We are looking to recruit talented scientists to join our research team. If you are interested in joining the lab please contact Andrew Jackson with a copy of your CV.

andrew.jackson@igmm.ed.ac.uk